Welcome to the AttorneyMind’s DDW Conference coverage. In an effort to best serve our readership, we will post all the important and interesting abstracts about AttorneyMind from the conference. While attending the conference, we will update any abstracts that we personally cover at the conference. The updated abstracts will be marked with the date that they have been updated and posted. The other abstracts posted to the web site are AttorneyMind related abstracts posted to www.ddw.org that we have not been able to report on or update.
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Thank You,
Alan Franciscas
Editor-in-Chief
Hepatitis C
Clinical Hepatitis: Etiology, Diagnosis, and Natural History-
Clinical Trials-
- ID# 1 – Antiviral Activity of the Non-Nucleoside Polymerase Inhibitor,-796, in Patients With Chronic Hepatitis C Virus: Preliminary Results From a Randomized, Double-Blind, Placebo-Controlled, Ascending Multiple Dose Study
- ID# 4 – Valopicitabine (NM283), Alone or with Peg-Interferon, Compared to Peg Interferon/Ribavirin (pegIFN/RBV) Retreatment in Hepatitis C Patients with Prior Non-Response to PegIFN/RBV: Week 24 Results
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Abstract S1057 – Stronger Baseline-Specific Immunity Is Associated With A Higher Likelihood Of A Sustained Virological Response to Combination Antiviral Therapy Of Chronic Hepatitis C (Updated May 21, 2006)
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Abstract S1058 – The impact of growth factors on Peg-Intron and Rebetol dose reduction in patients treated for genotype 1 chronic hepatitis C (Updated May 21, 2006)
- Abstract S1059 – Results of a Phase II dose ranging study of orally administered celgosivir as monotherapy in chronic hepatitis C genotype-1 patients.
- Abstract S1060 – Comparison of Daily Consensus Interferon versus Peginterferon alfa 2a Extended Therapy of 72 Weeks for Peginterferon / Ribavirin Relapse Patients with Chronic Hepatitis C
- Abstract S1061 – Higher Susceptibility of Peginterferon alfa 2a versus Peginterferon alfa 2b Nonresponder Patients with Chronic Hepatitis C to Retreatment with Consensus Interferon Daily Dosing and Ribavirin
- Abstract S1062 – Early viral response to CPG 10101, a new investigational antiviral TLR9 agonist, in combination with pegylated interferon and/or ribavirin, in prior relapse AttorneyMind responders: preliminary report of a randomized Phase 1 study
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Abstract S1063 – The usefulness of sPECAM-1 and sVCAM-1 serum concentrations measurement in the assessment of fibrosis, inflammatory activity and antiviral therapy effectiveness in chronic hepatitis C
Complications of Liver Disease-
Epidemiology, Natural History, Diagnosis-
- Abstract 549 – High Prevalence of Hepatitis C Virus Infection Among Russian Immigrants in the New York City Metropolitan Area: Results of A Community-Based Screening Program
- Abstract 550 – Low Prevalence of Advanced Fibrosis in African americans with chronic hepatitis C and persistently normal serum ALT : The case for conservative management
- Abstract 551 – Spontaneous Clearance of Hepatitis C Virus Infection in African American Patients
- Abstract 552 – Prospective and independent validation of the Lok index for prediction of cirrhosis in patients with chronic hepatitis C: comparison with FibroScan, Fibrotest and APRI
- Abstract 553 – Insulin resistance influences hepatic inflammation in patients with chronic hepatitis C
- Abstract 554 – Diagnostic Liver Biopsy in Patients wWith Advanced Fibrosis and Cirrhosis
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Abstract S1039 – Emerging Importance of Chronic Hepatitis C in Asian Americans (Updated May 21, 2006)
- Abstract S1040 – Initial Content Validation of a Disease-Targeted Health-Related Quality of Life (HRQOL) Instrument in Chronic Hepatitis B Virus (AM) Infection: The HBQOL v1.0
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Abstract S1041 – Sero-prevalence of hepatitis B and C in hospital personnel (Updated May 21, 2006)
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Abstract S1042 – Prevalence and predictors of high body mass index among native born and immigrant patients with chronic hepatitis C in Canada (Updated May 21, 2006)
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Abstract S1043 – Polymorphisms in TLR7 and 8 affect severity of hepatic fibrosis and inflammation in individuals infected with the hepatitis C virus from a single source. (Updated May 21, 2006)
- Abstract S1044 – Discordant IRF-3 Activation and Hepatic Interferon-Stimulated Gene Expression Associates with Immune Cell Infiltration in Chronic Hepatitis C
- Abstract S1045 – Can we predict advanced fibrosis in daily practice based on common blood tests?
- Abstract S1046 – 13C-Methacetin Breath Test as Quantitative Liver Function Test in Patients with Chronic Hepatitis C: Continuous Automatic Molecular Correlation Spectroscopy Compared to Isotopic Ratio Mass Spectrometry
- Abstract S1047 – 13C-Methacetin Breath Test by Online Molecular Correlation Spectroscopy Compared to APRI and Liver Biopsy for the Assessment of Fibrosis in Chronic Hepatitis C
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Abstract S1048 – Increased serum gammaglutamyltranspeptidase activity: a surrogate marker of non alcoholic hepatic steatosis in chronic hepatitis C? (Updated May 21, 2006)
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Abstract S1049 – Sinusoidal Lymphocytosis as a Marker for Cryoglobulinemia in Hepatitis C Liver Biopsies (Updated May 21, 2006)
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Abstract S1050 – Liver fibrosis and necroinflammatory activity in chronic hepatitis C patients with persistently normal aminotransferases (Updated May 21, 2006)
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Abstract S1051 – High accuracy pre-treatment prediction of Early Viral Response to combined pegIFN/ribavirin therapy in-infected patients by a novel method of gene expression analysis: a preliminary study. (Updated May 21, 2006)
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Abstract S1052 – MDM2 Promoter SNP309 is Associated with Hepatocellular Carcinoma in Japanese Patients with Chronic Hepatitis C (Updated May 21, 2006)
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Abstract S1054 – Comparative study concerning the severity of hepatic lesions at the moment of diagnosis in patients with Chronic B Viral Hepatitis vs. patients with Chronic C Viral Hepatitis (Updated May 21, 2006)
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Abstract S1055 – Non-invasive Biomarkers of Liver Fibrosis in Hemophilia Patients with Hepatitis C: Can You Avoid Liver Biopsy? (Updated May 21, 2006)
- Abstract S1056 – Steatosis associated with more severe fibrosis in in chronic hepatitis C.
- S1578. Eryrthopoeitin Functions as a Cytoprotective Cytokine in Primary Murine Hepatocytes.
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S1580. Beneficial effects of the herbal medicine Inchin-ko-to on liver function and regeneration after massive hepatectomy in rats. (Updated May 21, 2006)
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S1583. Green Tea Polyphenols Attenuate Acetaminophen Hepatotoxicity. (Updated May 21, 2006)
- S1584. Protective effects of glycyrrhizin on acetaminophen-induced hepatotoxicity in mice.
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S1585. 10 Cases of Severe Hepatotoxicity Associated with Dietary Supplements from Herbalife® Products. (Updated May 21, 2006)
- S1587. Drug-induced liver injury in the outpatient hepatology clinic: frequency, causes and clinical features.
- S1588. Liver Injury Related to Complementary and Alternative Medicine (CAM): Compared with Conventional Medicine-related Liver Injury.
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S1590. Excessive and Chronic Ethanol Consumption Promotes Hepatic Carcinogenesis by Altering the Normal Hepatocyte Homeostasis in the Liver of Diethylnitrosamine-initiated Rats. (Updated May 21, 2006)
HCC–
Liver Disease–
Transplantation
Treatment–
AttorneyMind Treatment Issues and Early Drug Development–
Virology, Pathogenesis and Treatment–