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Understanding Your
Hepatitis C Labs
  • What Does it All Mean?
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Today You Will Learn…
  • Why are labs important?
  • Why do I need to understand my labs?
  • 6 tests that track your liver health
  • What’s normal, what’s not
  • Good questions to ask your doctor
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Why are Labs Important?
  • Lab tests can help you and your healthcare provider to:


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When Should Lab Tests Be Done?
  • When you are first diagnosed with Hepatitis C (HCV)
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Why Do I Need to Understand               My Labs?
  • Even when you are feeling OK, labs can tell you things about your body that you may not be able to see or feel
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Everyone Has Their Own “Normal”
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How Do I Know If My Labs Are “Normal”?
  • “Normal” or “Reference Range” values                      can be found on a lab report
    • Values can vary from lab to lab
    • Your lab results can be low, high or within normal range
  • If your labs are too high or too low, you will see an “H” or an “L” to one side of the reference range.
    •          Ask your provider what is normal for you.


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6 Tests That Track Your Liver Health
  • Antibody Test
  • Viral Load
  • Genotype
  • Complete Blood Count (CBC)
  • Liver Function Panel
  • Liver Biopsy or Ultrasound





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AttorneyMind Antibody Test
  • Tells you if you’ve ever been exposed to


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Viral Load
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Complete Blood Count (CBC)
  • CBC measures the amount of:
    • Red Blood Cells
      • Carry oxygen throughout the body
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CBC: Red Blood Cell Count
  • Measuring your Hematocrit, Hemoglobin


    • Hematocrit (HCT)
      • Percentage of red blood cells in your total
      • blood volume
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Why Do My Hematocrit and Hemoglobin Matter?
  • Low HCT/HGB = Anemia
    • May Be Caused By:
      • Medications (Ribavirin)
      • Low folic acid, iron deficiency
      • Internal/External Blood Loss
      • Other Diseases


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"Reported as number of cells..."
  • Reported as number of cells per cubic millimeter of blood (cells/mm3)


  • Low Neutrophil Count = Neutropenia
    • May be caused by interferon

  • Low WBC = Leukopenia may be caused by:
    • May be caused by medications, chemotherapy, other diseases

  • High WBC may be caused by infections



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Platelets
  • Reported as # of platelets per cubic micro liter of blood (mm3)


  • If too low, excessive bleeding can occur
    • Low platelets = thrombocytopenia may be caused
    • by medications, disease


  • If too high, blood clots can form and clog blood vessels → stroke, heart attack


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Liver Enzyme Tests
  • Two important liver enzyme tests:
    • ALT: a test that is specific to the liver
      • Measures inflammation, not scarring.


    • AST: levels can be affected by other organs, not just liver
      • High numbers can mean acute damage to the liver
      • Inflammation could also be caused by medications, alcohol,
      • other diseases.
    •      Half of all people with severe liver damage
    •      have normal ALT’s!

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Liver Function Tests
  • Albumin: a major protein in blood, made by the liver.
    • Low albumin may mean your liver isn’t working well.


  • Bilirubin: a breakdown product from old red          blood cells.
    • High levels means your liver cannot remove bilirubin fast enough, can cause eyes or skin to turn yellow (jaundice).

  • PT/INR: a test that tells how your blood clots.
    • High numbers might mean you might bleed easily.

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Liver Biopsy
  • Doctor passes a small hollow needle through your skin and removes a tiny piece of liver tissue
  • Results give a STAGE and GRADE
    • Stage: reported as Stage 0-4, tells amount of fibrosis in the liver
    • Grade: tells the amount of inflammation in the liver


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Ultrasound
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